Genizer Machinery - High Pressure Homogenizer

  The NanoGenizer Core Processing Unit   The NanoGenizer is a laboratory scale high-pressure homogenizer. There are two segments of the NanoGenizer, the power unit and the core processing unit. The core processing unit is where homogenization occurs. Before homogenization, the user places the sample in the inlet reservoir. Genizer offers a variety of options for your inlet reservoir. You may prefer a smaller or larger inlet reservoir depending upon the size of your sample. In addition to stainless steel, we offer plastic syringes and glass inlet reservoirs. Genizer also offers a variety of outlet reservoirs, where the sample goes after processing. You may prefer to use a jacketed glass cylinder, which you can connect to a laboratory chiller circulator for temperature control. Schematic of the NanoGenizer core processing unit,with the inlet reservoir, high-pressure pump, interaction chamber, heat exchanger and outlet reservoirFor small, valuable samples, the syringe option is b...

How to Properly Use a High Pressure Homogenizer ? High-pressure homogenizers are indispensable tools across various industries, including pharmaceuticals, food processing, and biotechnology. They perform a range of tasks, from cell disruption to particle size reduction. To ensure both efficient and safe operation, it is essential to have a thorough understanding of how to properly use a high-pressure homogenizer. In this article, we will provide a comprehensive guide, focusing on the essential steps for effective utilization. 1.  Understanding the Basics To begin, let's delve deeper into the core components and functionalities of a high-pressure homogenizer. A typical high-pressure homogenizer comprises a pump, a homogenization chamber, and various valves and connectors. The pump serves as the workhorse, generating the immense pressure required for the homogenization process. The homogenization chamber, often a microfluidic interaction chamber, is the stage where this process unfol...

Benefits of UltraGenizer High Pressure Homogenizers UltraGenizer Microfludic High Pressure Homogenizers represent a notable advancement when it comes to achieving precise and efficient homogenization of various materials. Designed to meet the demands of cutting-edge research and industrial applications, these homogenizers offer a host of benefits that set them apart. Let's delve into the advantages that make UltraGenizer stand out:   UltraGenizer Microfluidic High Pressure Homogenizer 1.  Unmatched Pressure Control:  With a maximum design pressure of 60,000 psi, UltraGenizer allows users to fine-tune the pressure  settings through an  intuitive touchscreen interface , ensuring easy and user-friendly operation. 2.  High-Performance Flow Rate : The homogenization flow rate can reach a maximum of 100 ml/min, providing exceptional flexibility and adaptability for different materials and viscosities. 3.  Customizable Sample Intake : UltraGenizer enable...

High-pressure homogenizers play a pivotal role in various domains, including scientific research, pharmaceutical manufacturing, cosmetics, and food processing. Opting for an appropriate high-pressure homogenizer is crucial to ensure optimal experimental outcomes and resource efficiency. Here are several key factors to consider when selecting the most suitable high-pressure homogenizer:   Genizer High Pressure Microfluidic Homogenizers 1.     Homogenization Pressure: Maximizing Performance by Optimizing Pressure Increasing pressure allows for finer particle size reduction, enabling efficient processing. Higher pressures accommodate a broader range of materials for effective homogenization. For example, certain liquid emulsions require a minimum pressure of 15,000 psi to achieve sub-100nm homogenization, while achieving nanoscale homogenization for pharmaceuticals, foods, and suspensions with solid particles typically demands pressures exceeding 26,000 psi. ...

  When it comes to particle size reduction, emulsion formation, and cell disruption, two commonly used equipment options are high-pressure homogenizers (conventional valve homogenizers)and microfluidizers (cutting-edge high pressure microfluidic homogenizers ). These technologies excel at achieving consistent particle size distribution and enhancing product quality across various industries. In this comparison, we will explore the differences between high-pressure homogenizers and microfluidizers, highlighting their unique features, advantages, and important considerations. By the end, you will have the knowledge needed to make an informed decision when selecting the appropriate equipment.   High-Pressure Homogenizers (conventional valve homogenizers): High-pressure homogenizers are robust machines that utilize high pressure and mechanical forces to process materials. They consist of a piston-driven homogenizing valve, which propels the sample through a narrow gap, resul...

Homogenization is a crucial step in various industrial processes, including pharmaceuticals, food, and cosmetics.  High-pressure homogenization  (HPH) and sonication are two common homogenization techniques, but HPH offers several distinct advantages over sonication, especially when used with Genizer's high-pressure homogenizers . Genizer High-Pressure Homogenizer Smaller Particle Sizes One of the most significant advantages of HPH over sonication is its ability to produce smaller particle sizes. HPH operates at much higher pressures and forces the sample through a narrow valve, resulting in a more intense and efficient homogenization process. This leads to smaller particle sizes, which can improve product quality, increase bioavailability, and enhance downstream processing steps such as filtration or extraction. Samples before and after homogenization using  NanoGenizer microfluidic high-pressure homogenizers ...

Choosing between a high-pressure homogenizer or a liposome extruder for your liposomes Choosing between a high-pressure homogenizer or a liposome extruder for your liposomes can be a daunting task. Both devices have their advantages and can process liposomes, but the choice ultimately depends on your specific application requirements. Option 1: High-Pressure Homogenizer The NanoGenizer high-pressure homogenizer is a powerful device that is easy to operate. It is electrically powered, making it simple to plug into the wall and start processing your liposomes. One of the major advantages of the NanoGenizer is its faster flow rate , allowing for quicker processing times. Additionally, the NanoGenizer is less likely to jam compared to a liposome extruder, improving the overall efficiency of your liposome preparation process. Option 2: Liposome Extruder If accuracy is a priority for your liposome preparation process, a jacketed liposome extruder might be the better option for ...