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Showing posts with the label HPH

Microjet NanoGenizer and Micromix MixGenizer: the next generation homogenizer for nanomaterials

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Microjet technology is a method for producing nanomaterials in high-pressure fluid jets, enabling the scalable and efficient production of nanomaterials. In the vast field of manufacturing, an 'industrial mother machine' refers to equipment crucial for producing other machines or products. Nanomaterials, key raw materials for various functional products, find broad applications, and the NanoGenizer Microjet Homogenizer is one such device widely used in the preparation of nano-drug formulations and various emerging nanomaterials, making it a leading industrial mother machine for next-generation nanomaterials. High-pressure Micromix technology is an extension of M icrojet technology, where the Micromix   MixGenizer  High-Pressure Homogenizer generates nanomaterials by precisely controlling multiphase mixing. These two devices play fundamental and crucial roles in the production of advanced nanomaterials, holding significant importance in driving the entire field of nanotechnology

Using High-Pressure Microfluidic Homogenizers for Micro and Nano Emulsions

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High-pressure homogenization, especially in the context of creating microemulsions and nanoemulsions, stands as a pioneering innovation that transcends multiple industries. These ultra-fine emulsions, characterized by droplet sizes typically below 100 nanometers, offer a myriad of advantages. In this article, we will explore the unique benefits of harnessing high-pressure microfluidic homogenizers for the formulation of microemulsions and nanoemulsions.   Advantages of High-Pressure Microfluidic Homogenizers   High-pressure microfluidic homogenizers deliver a range of distinctive advantages when applied to the production of microemulsions and nanoemulsions:   Precision in Particle Size Control:   These homogenizers offer meticulous control over particle size reduction, ensuring droplets measure at or below 100 nanometers.   Consistent Dispersion : High-pressure microfluidic homogenizers ensure even dispersion, resulting in emulsions of remarkable stability.   Extended Shelf Life : The

How does NanoGenizer High-Pressure Homogenizer work?

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  The NanoGenizer Core Processing Unit   The NanoGenizer is a laboratory scale high-pressure homogenizer. There are two segments of the NanoGenizer, the power unit and the core processing unit. The core processing unit is where homogenization occurs. Before homogenization, the user places the sample in the inlet reservoir. Genizer offers a variety of options for your inlet reservoir. You may prefer a smaller or larger inlet reservoir depending upon the size of your sample. In addition to stainless steel, we offer plastic syringes and glass inlet reservoirs. Genizer also offers a variety of outlet reservoirs, where the sample goes after processing. You may prefer to use a jacketed glass cylinder, which you can connect to a laboratory chiller circulator for temperature control. Schematic of the NanoGenizer core processing unit,with the inlet reservoir, high-pressure pump, interaction chamber, heat exchanger and outlet reservoirFor small, valuable samples, the syringe option is best. You

How to choose a high pressure homogenizer for your applications?

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High-pressure homogenizers play a pivotal role in various domains, including scientific research, pharmaceutical manufacturing, cosmetics, and food processing. Opting for an appropriate high-pressure homogenizer is crucial to ensure optimal experimental outcomes and resource efficiency. Here are several key factors to consider when selecting the most suitable high-pressure homogenizer:   Genizer High Pressure Microfluidic Homogenizers 1.     Homogenization Pressure: Maximizing Performance by Optimizing Pressure Increasing pressure allows for finer particle size reduction, enabling efficient processing. Higher pressures accommodate a broader range of materials for effective homogenization. For example, certain liquid emulsions require a minimum pressure of 15,000 psi to achieve sub-100nm homogenization, while achieving nanoscale homogenization for pharmaceuticals, foods, and suspensions with solid particles typically demands pressures exceeding 26,000 psi.   2.     Minimal Sa

High Pressure Homogenizer VS Microfluidizer, How to Choose?

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  When it comes to particle size reduction, emulsion formation, and cell disruption, two commonly used equipment options are high-pressure homogenizers (conventional valve homogenizers)and microfluidizers (cutting-edge high pressure microfluidic homogenizers ). These technologies excel at achieving consistent particle size distribution and enhancing product quality across various industries. In this comparison, we will explore the differences between high-pressure homogenizers and microfluidizers, highlighting their unique features, advantages, and important considerations. By the end, you will have the knowledge needed to make an informed decision when selecting the appropriate equipment.   High-Pressure Homogenizers (conventional valve homogenizers): High-pressure homogenizers are robust machines that utilize high pressure and mechanical forces to process materials. They consist of a piston-driven homogenizing valve, which propels the sample through a narrow gap, resulting in i

High-Pressure Homogenization vs. Sonication: Choosing the Right Method for Your Application

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Homogenization is a crucial step in various industrial processes, including pharmaceuticals, food, and cosmetics.  High-pressure homogenization  (HPH) and sonication are two common homogenization techniques, but HPH offers several distinct advantages over sonication, especially when used with Genizer's high-pressure homogenizers . Genizer High-Pressure Homogenizer Smaller Particle Sizes One of the most significant advantages of HPH over sonication is its ability to produce smaller particle sizes. HPH operates at much higher pressures and forces the sample through a narrow valve, resulting in a more intense and efficient homogenization process. This leads to smaller particle sizes, which can improve product quality, increase bioavailability, and enhance downstream processing steps such as filtration or extraction. Samples before and after homogenization using  NanoGenizer microfluidic high-pressure homogenizers     Scalab

Liposome Processing: High-Pressure Homogenizer or Liposome Extruder?

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Choosing between a high-pressure homogenizer or a liposome extruder for your liposomes Choosing between a high-pressure homogenizer or a liposome extruder for your liposomes can be a daunting task. Both devices have their advantages and can process liposomes, but the choice ultimately depends on your specific application requirements. Option 1: High-Pressure Homogenizer The NanoGenizer high-pressure homogenizer is a powerful device that is easy to operate. It is electrically powered, making it simple to plug into the wall and start processing your liposomes. One of the major advantages of the NanoGenizer is its faster flow rate , allowing for quicker processing times. Additionally, the NanoGenizer is less likely to jam compared to a liposome extruder, improving the overall efficiency of your liposome preparation process. Option 2: Liposome Extruder If accuracy is a priority for your liposome preparation process, a jacketed liposome extruder might be the better option for