How to choose a high pressure homogenizer for your applications?

High-pressure homogenizers play a pivotal role in various domains, including scientific research, pharmaceutical manufacturing, cosmetics, and food processing. Opting for an appropriate high-pressure homogenizer is crucial to ensure optimal experimental outcomes and resource efficiency. Here are several key factors to consider when selecting the most suitable high-pressure homogenizer:

 

Genizer High Pressure Microfluidic Homogenizers

1.    Homogenization Pressure: Maximizing Performance by Optimizing Pressure

Increasing pressure allows for finer particle size reduction, enabling efficient processing. Higher pressures accommodate a broader range of materials for effective homogenization. For example, certain liquid emulsions require a minimum pressure of 15,000 psi to achieve sub-100nm homogenization, while achieving nanoscale homogenization for pharmaceuticals, foods, and suspensions with solid particles typically demands pressures exceeding 26,000 psi.

 

2.    Minimal Sample Volume: Enhancing Efficiency through Material Conservation

Minimizing sample volume helps conserve expensive raw materials, especially considering the high cost of specific pharmaceutical ingredients (several thousand dollars per gram). Since experiments often involve multiple iterations, larger minimum sample volumes lead to significant material waste.

 

3.    Processing Effectiveness: Achieving Nano-Level Precision and Uniform Particle

Size Distribution Desirable outcomes involve attaining nanoscale particle size and ensuring uniform particle size distribution. To address this, it is advisable to acquire a high-pressure homogenizer equipped with a nano-level filtration extruder device, preferably an inline extruder, to enhance processing effectiveness.

 

4.    Cleaning and Sterilization: Optimizing Maintenance and Sanitization

Some high-pressure homogenizers offer convenient cleaning and sterilization procedures. Prioritizing models that facilitate online cleaning and sterilization is recommended.

 

5.    Additional Considerations: Noise, Safety, and Reputation

Evaluate factors such as noise levels, safety features, and the reputation of the homogenizer. Analyzing customer lists can provide insights into the popularity and quality of a particular device.

 

6.    Manufacturer Validation: Customer References and Supporting Evidence Request a

customer reference list from homogenizer manufacturers to assess customer satisfaction. Additionally, inquire about relevant research papers and achievements to further evaluate the equipment's credibility.

 

By thoroughly considering these factors, potential users can make well-informed comparisons and select the most suitable high-pressure homogenizer based on their specific requirements.