High Pressure Homogenizer | Genizer Machinery

NanoGenizer High Pressure Homogenizer:

NanoGenizer is a laboratory high pressure processing device. It is an electrically-driven and bench-top, high pressure homogenizer requiring no compressed air or hydraulic oil to achieve maximum 3,062 bar (45,000 psi) operating pressure. NanoGenizer high pressure homogenizer is composed of a feed reservoir, high pressure pump, transducer, PLC control panel and microfluidics diamond interaction chamber. The sanitary pump system of the NanoGenizer high pressure homogenizer is able to supply the desired pressure to the product stream and push it through the micron chamber (microreactor) to create high shear rates and strong impact within the stream. This process results in uniform particle distribution and smaller particle sizes.

Application of NanoGenizer High Pressure Homogenizer:

Cell disruption and particle size reduction Nanoemulsions  Nano dispersions Liposomes Deagglomeration

Performance of NanoGenizer High Pressure Homogenizer:

Energy efficient, 1/2 energy loss of the most homogenizers Small (integrated design delivers the light weight and small dimensions) Smart (programming control systems confer diligent functions: controlled inlet volume ± 0.1mL; auto stop with time/volume) Silent (noiseless performance) Strong (more than 150 mL/min at 30,000 psi) CE compliant and RoHs compliant Specifications Catalog No. NG-45K  NG-30K NG-25K NG-20K NG-15K Flow Rate 60mL/min 100mL/min 100mL/min 150mL/min 150mL/min Min. Sample 5mL 5mL 5mL 5mL 5mL Max. Pressure 45,000psi 30,000psi 25,000psi 20,000psi 15,000psi Dimensions(cm) 70 × 36 × 30 70 × 36 × 30 70 × 36 × 30 70 × 36 × 30  70 × 36 × 30 Weight 35 kg (75 lbs) 35 kg (75 lbs) 35 kg (75 lbs) 35 kg (75 lbs) 35 kg (75 lbs) Max. Temp. 80ºC (176ºF) Power 110V/220V Cleaning Flush to clean Application Nano emulsion, fat emulsion, liposome, cell disruption, nano dispersion, deagglomeration Features Digital display of pressure or pressure gauge   Standard Features Parts Y-type diamond interaction chamber with cooling option Control System High pressure programming control systems: touch screen, speed control, auto stop control by volume, time, pressure or temperature, settable volume control as low as 1mL, display of flow rate and time, overload protection Pressure Gauge Digital display on the touch screen Inlet Type 1/4" HP coupling Outlet Type 1/4" HP coupling Inlet Reservoir 20mL syringe Outlet Reservoir 20mL syringe Product Material 316L stainless steel, tungsten carbide, viton, teflon Material Standard Sanitary grade, FDA, GMP Warranty 1 year against any manufacturing defects   Option Features Parts High pressure extruders, homogenizing valves two stages, heat exchanger Control System Mechanical control: speed, start, stop control Detector Pressure gauge, pressure transducer, temperature transducer Outlet Type Tri-clamp or luer Heat Exchanger HPE-100-3D; HPE-150-3D; HPE-200-3D Liposome Extruder GOE-200mL; GOE-1000mL Inlet Reservoir 10mL, 20mL, 50mL, 100mL, 200mL, 500mL syringe, S/S cylinder, jacketed glass cylinder or online Outlet Reservoir 10mL, 20mL, 50mL, 100mL, 200mL, 500mL syringe, S/S cylinder, jacketed glass cylinder or online Cylinder Titanium high pressure cylinder (resistant to strong acid and base)   Product Introduction and User Guide Video Sharing: user guids of genizer highpressure homogenizers Introduces the structure and operation of the microjet high-pressure homogenizer   Varieties of Inlet and Outlet for NanoGenizer Inlet:  syringe; open container; stainless steel cylinder Outlet: syringe; open container; stainless steel cylinder Genizer Diamond Interaction Chambers for High Pressure Homogenizers Y-Type Diamond Interaction Chamber (DIXC) is used to produce uniform nanoparticles in a high pressure homogenizer. The fixed geometry within the Y-Type DIXC is intended to create a uniform processing profile so that all materials will be processed with equal disruptive forces. Single-slotted interaction chambers have a single microchannel and are ideal choices for small batch research, while the multi-slotted interaction chamber comprises multiple microchannels in parallel, which can be used at industrial scales, by increasing the flow rate through the DIXC but with equal processing forces.   Application: Nanoemulsion, cell disruption, nanodispersion, deagglomeration, liposome   Performance: Full replacement for the chamber of Microfluidizer processors Electro-polishing and inner passivation for pharmaceutical applications Real-time cooling option to reduce oversized particles Lower cost and higher quality   Specifications Description Y-type diamond interaction chamber single-slotted, multi-slotted Brand GenizerTM with high quality Compatibility with Microfluidizer, Avestin EmulsiFlexs, PSI Single-slotted: M-110Y, M-110P, M-110L, M-110S and M-110EH, PSI-20, adapt to Avestin EmusiFlxe-C3 Multi-slotted: M-7115, M-7125, M-7250, M210, M610, PSI-40 Dimensions W × D × H 35mm × 35mm × 85mm (single-slotted) 45mm × 45mm × 200mm (multi-slotted) 95mm × 95mm × 300mm (9/16" F→9/16" M multi-slotted) Weight 1 lbs. (0.5kg) (single-slotted) 3 lbs. (1.5kg) (multi-slotted) 15 lbs. (7.0kg) (M610) Cleaning Flush to clean Sterilization Whole unit autoclavable Pressure Range 20,000 psi; 30,000 psi; 45,000 psi Chamber Type Available Single-slotted: F12Y, F20Y and static homogenizing valve Multi-slotted: F12Y-4, F12Y-5, F12Y-6, F12Y-7, F20Y-2, F20Y-4, F20Y-6, F20Y-7, F20Y-12, F20Y-13, F20-Y-17   Standard Features Chamber Type Y-type diamond interaction chamber: F12Y, F20Y, N40Y, J30Y, J20Y for M210, F30Y, H230Y, F20Y-12, F20Y-13, F20-Y-14 for M610 Max. Pressure 30,000 psi Product Material 316L stainless steel, diamond Polishing Condition Electro-polish and passivation for pharmaceuticals Warranty 1 year against any manufacturing defects   Option Features Chamber Type Z-type diamond interaction chamber: H10Z, G10Z, H30Z, H210Z, H230Z, Q50Z, T50Z, T60Z, APM diamond auxiliary processing modules (APM) Customer Made Customized laser mark, dimensions and fittings Max. Pressure 45,000 psi Product Material Titanium (resistant to strong acid and base) Product Cooling Real time cooling on chamber   Upgrade to Y-Type Diamond Interaction Chamber  Upgrade used F12Y or F20Y chamber to F12Y-RT or F20Y-RT diamond chamber with real-time cooling function. Promotion available for a limited time.   Original Chamber Upgrade to Brand New Price F12Y or F20Y diamond single-slotted chamber F12Y-1-RT or F20Y-1-RT diamond chamber Quote F12Y or F20Y ceramic single-slotted F12Y-1-RT or F20Y-1-RT diamond chamber Quote F12Y or F20Y multi-slotted chamber F12Y-RT or F20Y-RT multi-slotted diamond chamber Quote Genizer Machinery | Liposome Extruder  Description: The HandExtruder is a manually powered extruder designed for the formulation of 0.25mL-2.0mL liposome and lipopolyplex with small samples. The sample is passed back through the membrane by being pushed back and forth between two syringes. Homogenous samples can be produced quickly and easily in minutes; typically 5-10 passes are sufficient to produce a sample with uniform liposome size. The HandExtruder offers minimal dead-volume, is easy to clean and is suitable for sterilization. Temperature control is available.   Application: Liposome extrusion   Performance: Low dead volume HandExtruder-1mL-RT can increase the temperature   Specifications Catalog No. HandExtruder-1mL  HandExtruder-1mL-RT Description Liposome hand extruder Liposome hand extruder with thermo-jacket Cooling None Yes Dimensions 23cm×17cm×13cm 23cm×17cm×13cm Weight 2kg 2kg Application Liposome formulation Lipids with high transition temperature or heat-sensitive Min. Sample Size 0.25mL Max. Pressure 700 psi Temperature Limit 80ºC (176ºF) Power Type Manual Nano-membrane 19mm polycarbonate membrane Cleaning Flush to clean Sterilization Whole unit autoclavable   Standard Features Parts 1) Liposome HandExtruder 2) 10 pieces of 100nm/400nm/other size membrane Feed Reservoir 1.0 mL gas-tight syringe Collector Reservoir 1.0 mL gas-tight syringe Nano Membrane 100nm 19mm track-etched polycarbonate membrane Compatibility Parts are compatible with Liposofast in Avestin Product Material 316L stainless steel, viton Material Standard Sanitary grade Warranty 1 year against any manufacturing defects   Option Features Parts Stabilizer holder for HandExtruder Feed Reservoir 0.25/0.5/1.0/2.5mL gas-tight syringe Collector Reservoir 0.25/0.5/1.0/2.5mL gas-tight syringe Nano Membrane 30, 50, 80, 100, 200, 400, 800nm, 1000nm, 2μm, 5μm, 10μm, 20μm, 30μm 19mm track-etched membrane Syringe Type Gas-tight syringe with protective film   Product Introduction and User Guide Video Sharing: Introduction of HandExtruder How to make liposome with HandExtruder