Genizer Machinery - High Pressure Homogenizer

Homogenization is a crucial step in various industrial processes, including pharmaceuticals, food, and cosmetics.  High-pressure homogenization  (HPH) and sonication are two common homogenization techniques, but HPH offers several distinct advantages over sonication, especially when used with Genizer's high-pressure homogenizers . Genizer High-Pressure Homogenizer Smaller Particle Sizes One of the most significant advantages of HPH over sonication is its ability to produce smaller particle sizes. HPH operates at much higher pressures and forces the sample through a narrow valve, resulting in a more intense and efficient homogenization process. This leads to smaller particle sizes, which can improve product quality, increase bioavailability, and enhance downstream processing steps such as filtration or extraction. Samples before and after homogenization using  NanoGenizer microfluidic high-pressure homogenizers ...

Choosing between a high-pressure homogenizer or a liposome extruder for your liposomes Choosing between a high-pressure homogenizer or a liposome extruder for your liposomes can be a daunting task. Both devices have their advantages and can process liposomes, but the choice ultimately depends on your specific application requirements. Option 1: High-Pressure Homogenizer The NanoGenizer high-pressure homogenizer is a powerful device that is easy to operate. It is electrically powered, making it simple to plug into the wall and start processing your liposomes. One of the major advantages of the NanoGenizer is its faster flow rate , allowing for quicker processing times. Additionally, the NanoGenizer is less likely to jam compared to a liposome extruder, improving the overall efficiency of your liposome preparation process. Option 2: Liposome Extruder If accuracy is a priority for your liposome preparation process, a jacketed liposome extruder might be the better option for ...

What is homogenization? Homogenization, or homogenisation, is any of several processes used to make a mixture of two mutually non-soluble liquids the same throughout. This is achieved by turning one of the liquids into a state consisting of extremely small particles distributed uniformly throughout the other liquid. In other words, homogenization is the process of converting two immiscible liquids into an emulsion.  Genizer homogenization technology applies a microfluidics Diamond Interaction Chamber (DIXC) to produce uniform nanoparticles in high shear homogenizers. The processed fluid passes through the fixed geometry within the Y-type and Z-type microfluidics chamber (which can also be considered a continuous microreactor) to create a uniform processing profile. Through this method, oil-in-water and water-in-oil nanoemulsions (100–1000 nm) can be produced. High pressure nozzel, impact valve or microfludics chamber (microreactor)? High pressure homogenization process pumps ...

  Liposome Extruders   Instrument : Genizer Liposome Extruders AKA : Exosomes Extruders, Artificial Cell Membrane Extruders; Liposomes Preparation devices by extrusion Advantages : Liposome extruders are mainly used for the liposome formulation and achieving uniform size distributions. It is an ideal instrument to generate nanoscale liposome formulations, and to prepare exosomes and artificial cell membranes. By utilizing the tracked-etched filter membranes, the liposome extruders are capable of capturing large particles, precipitation and achieving sterile filtration. Application : Research and Development for the liposomal drug delivery system, vaccine, gene delivery, and cosmetics Working Principles:  A liposome is a spherical-shaped vesicle composed of phospholipid bilayers. Phospholipid bilayers are critical components of cell membranes, with hydrophilic and hydrophobic properties. In an aqueous solution, the hydrophobic ends tend to bind to each other, and spontaneo...

  NanoGenizer High Pressure Homogenizer for Nanomaterials   NanoGenizer , a lab-scale microfluidic high pressure homogenizer, offers effective performance on particle size reduction and cell disruption. It utilizes interaction high-pres sure microfluidic jet technology, and equipped with highly modular power and processing units. NanoGenizer is suitable for rare and valuable samples because of its minimum dead volume design and its continuous flow rate, which enables it to process up to 120 mL/min. With successful applications in various nanotechnology settings, the NanoGenizer has gained increasing recognition due to its notable shear rate, excellent repeatability, and guaranteed scalability.   NanoGenizer provides efficient solutions for various nanomaterials, including: liposomes, nano-emulsions, nano-crystals, micelles, lipid nanoparticles, cosmetic nano-encapsulation materials, nano-particle dispersion, graphene, carbon nanotube, and more. As more organizations recog...