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Advancing Polymer Nanoparticle Drug Delivery with High-Pressure Microfluidization

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Polymer nanoparticles are increasingly central to modern drug delivery strategies. They protect active pharmaceutical ingredients (APIs), enable controlled release, and allow precise targeting. These systems are widely used in applications ranging from mRNA therapeutics to small-molecule drugs and diagnostic agents. Consistent particle size is essential. Uniform nanoparticles improve biodistribution, stability, filtration efficiency, and therapeutic safety. Challenges in Nanoparticle Production Producing polymer nanoparticles with uniform size and reproducibility is challenging. Traditional emulsification methods often face issues such as: Broad particle size distributions Batch-to-batch variability Difficulty scaling from laboratory to industrial production These challenges can compromise product performance and create regulatory hurdles when moving from research to clinical or commercial manufacturing. High-Pressure Microfluidization: A Reliable Solution High-pressu...