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Showing posts from March, 2023

Everything You Need to Know About Homogenization

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What is homogenization? Homogenization, or homogenisation, is any of several processes used to make a mixture of two mutually non-soluble liquids the same throughout. This is achieved by turning one of the liquids into a state consisting of extremely small particles distributed uniformly throughout the other liquid. In other words, homogenization is the process of converting two immiscible liquids into an emulsion.  Genizer homogenization technology applies a microfluidics Diamond Interaction Chamber (DIXC) to produce uniform nanoparticles in high shear homogenizers. The processed fluid passes through the fixed geometry within the Y-type and Z-type microfluidics chamber (which can also be considered a continuous microreactor) to create a uniform processing profile. Through this method, oil-in-water and water-in-oil nanoemulsions (100–1000 nm) can be produced. High pressure nozzel, impact valve or microfludics chamber (microreactor)? High pressure homogenization process pumps ...

What is Liposome Extruders?

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  Liposome Extruders   Instrument : Genizer Liposome Extruders AKA : Exosomes Extruders, Artificial Cell Membrane Extruders; Liposomes Preparation devices by extrusion Advantages : Liposome extruders are mainly used for the liposome formulation and achieving uniform size distributions. It is an ideal instrument to generate nanoscale liposome formulations, and to prepare exosomes and artificial cell membranes. By utilizing the tracked-etched filter membranes, the liposome extruders are capable of capturing large particles, precipitation and achieving sterile filtration. Application : Research and Development for the liposomal drug delivery system, vaccine, gene delivery, and cosmetics Working Principles:  A liposome is a spherical-shaped vesicle composed of phospholipid bilayers. Phospholipid bilayers are critical components of cell membranes, with hydrophilic and hydrophobic properties. In an aqueous solution, the hydrophobic ends tend to bind to each other, and spontaneo...

NanoGenizer High Pressure Homogenizer for Nanomaterials

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  NanoGenizer High Pressure Homogenizer for Nanomaterials   NanoGenizer , a lab-scale microfluidic high pressure homogenizer, offers effective performance on particle size reduction and cell disruption. It utilizes interaction high-pres sure microfluidic jet technology, and equipped with highly modular power and processing units. NanoGenizer is suitable for rare and valuable samples because of its minimum dead volume design and its continuous flow rate, which enables it to process up to 120 mL/min. With successful applications in various nanotechnology settings, the NanoGenizer has gained increasing recognition due to its notable shear rate, excellent repeatability, and guaranteed scalability.   NanoGenizer provides efficient solutions for various nanomaterials, including: liposomes, nano-emulsions, nano-crystals, micelles, lipid nanoparticles, cosmetic nano-encapsulation materials, nano-particle dispersion, graphene, carbon nanotube, and more. As more organizations recog...